Alphabetical listing of popular business hours in Rancho Santa Margarita:
- 24 Hour Fitness
- Aaron Brothers
- Banfield The Pet Hospital
- Bank Of America
- Baskin-Robbins
- Bed Bath & Beyond
- Big Lots
- BJ's Restaurant & Brewhouse
- Borders Books & Music
- Bruegger's Bagels Bakery
- Burger King
- Carl's Jr
- Chase Bank
- Chevron
- Chipotle Mexican Grill
- Cold Stone Creamery
- Curves
- CVS Pharmacy
- Del Taco
- Dickey's Barbecue Pit
- El Pollo Loco
- Exxon Mobil
- Fantastic Sams
- First Citizens Bank
- Great Clips
- Hertz Rent A Car
- IHOP
- In-N-Out Burger
- Jiffy Lube
- KFC
- Kohl's
- Lens Crafters
- McDonald's
- Menchie's Frozen Yogurt
- Panda Express
- Panera Bread
- Papa John's Pizza
- Pavilions
- Payless Shoe Source
- Penske Truck Rental